development of a method for aluminium determination in serum and dialysis fluid by flameless atomic absorption with graphite furnace

aluminium determination was carried out in serum and dialysis fluid by a simple and reliable method of nameless atomic absorption with graphite furnace . . no preparatory procedures are required for water and dialysis fluid. in this method serum was mixed with 0.2% hno, to allow complete combustion of the samples in order to improve analytical precision. the method has a sensitivity of 15 pg and detection limit of 2.1 µg ai/l. the aluminium contents of the main water supply, be-distilled water and dialysis fluid were 52, i, and 44 µg/l respectively. the mean value for normal serum aluminium in isfahan was 3.6 µg/l. serum aluminium concentration in chronic renal failure was measured in pre- and post-dialysis samples. the mean values for the serum aluminium levels pre- and post-dialysis were 30.5 and 71.08 µg/l with a range of 9-60 and 21-123 µg/l, respectively. pre- and post-dialysis serum aluminium values in female patients were within the range of 1-42 and 12- 66 µg/l with mean values of 18.25 and 40.5 µg/l, respectively. instrumental settings and sample handling are discussed.